One of the best results in recent years has given a method that allowed established by the Twenty cells from 10 000 source. The current group of scientists also said that they were able to convert 92% of primary adult cells into stem cells.
The specialists have created a genetically similar mouse immune system with extra copies of four genes. On the latter were "sewn" original switches, which under the influence of certain substances activate the work of those most genes.
In the first series of experiments, the researchers grew individual immune cells from the "on" genes. Scientists have watched their growth and division, controlling, there are signs of pluripotency. properties that determines the possibility of stem cell "get re" in any cell of the body.
Some populations have begun to produce a particular chemical signal of pluripotency, two weeks later, others - only after 18 weeks. "Virtually all cells have the opportunity to become a stem,"
Summarizing the data, the researchers make bold conclusion that the right conditions, any cell of an adult organism can be transformed into a state close to the properties of the stem. Previously it was thought that only certain types of fabrics give a good performance.
Researchers have been unable to determine why some cells are given their stem earlier and others later, but it is certainly not in the rate of division. One of the "suspects" was the gene NANOG . When the researchers increased its expression, pluripotent cells began to form earlier in fewer cycles of division.
The specialists have created a genetically similar mouse immune system with extra copies of four genes. On the latter were "sewn" original switches, which under the influence of certain substances activate the work of those most genes.
In the first series of experiments, the researchers grew individual immune cells from the "on" genes. Scientists have watched their growth and division, controlling, there are signs of pluripotency. properties that determines the possibility of stem cell "get re" in any cell of the body.
Some populations have begun to produce a particular chemical signal of pluripotency, two weeks later, others - only after 18 weeks. "Virtually all cells have the opportunity to become a stem,"
Summarizing the data, the researchers make bold conclusion that the right conditions, any cell of an adult organism can be transformed into a state close to the properties of the stem. Previously it was thought that only certain types of fabrics give a good performance.
Researchers have been unable to determine why some cells are given their stem earlier and others later, but it is certainly not in the rate of division. One of the "suspects" was the gene NANOG . When the researchers increased its expression, pluripotent cells began to form earlier in fewer cycles of division.
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